By Priv. Doz. Dr. Ernst Franzek, Univ.-Prof. Dr. Dr. h.c. Helmut Beckmann (auth.)
Contradictory leads to schizophrenia examine are normally defined as being as a result of genetic heterogeneity and a number of issue heredity in dating to manifold environmental components. The booklet stories a quick evaluation of all correct dual experiences on schizophrenic psychoses and offers information and case histories on a scientific dual examine in line with a polydiagnostic technique performed by means of independently operating psychiatrists. as well as the across the world utilized operational diagnostic platforms of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses used to be used. during the past this refined methodological method is exclusive on the planet. the information supply powerful facts that the spectrum of psychoses with schizophrenic and schizophrenia-like indicators isn't a continuum of illnesses. not less than in Leonhard’s 3 significant teams of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social components play a totally various etiological position. Cycloid psychoses and systematic schizophrenias are predominantly brought on by "environmental” components. In unsystematic schizophrenias, although, genetic predisposition is the most etiological issue and environmental components are subordinate.
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Additional info for Psychoses of the Schizophrenic Spectrum in Twins: A Discussion on the Nature — Nurture Debate in the Etiology of “Endogenous” Psychoses
The study is therefore based on a total of 47 same-sex twin pairs with at least one index-twin suffering from a psychosis of the schizophrenic spectrum. Zygosity. Blood samples for a molecular-genetic zygosity diagnosis could be taken from both partners in the case of 43 pairs. 6%). No blood samples could be obtained in the case of three pairs and the blood taken from one pair was not sufficient. The zygosity diag- 44 Results noses in these four cases are based solely on the questionnaire method and the similarity test.
Among the cycloid psychoses, nine of 11 monozygotic pairs with motility psychoses were concordant (82%). Of the two discordant pairs the ill index-twin was the second-born, more susceptible to mental strain and in one case suffered from severe asphyxia during birth. Among the concordant pairs no essential differences could be detected between the two partners based on the birth histories. In many cases, however, either one or both partners had suffered birth complications. In five of nine cases the second-born and mentally more unstable twin became ill earlier and/or more severely.
Concordance group C2. The co-twin is/was also psychotic, does/ did not suffer from the same but from a different psychosis within the schizophrenic spectrum. Concordance group C3. The co-twin does/did not suffer from a Determining the criteria for concordance/discordance 39 psychosis within the schizophrenic spectrum, but does/did suffer from another relevant psychiatric disorder with the exception of a demential disorder or mental retardation. Discordance D. The co-twin was never mentally ill and proved to be mentally normal and healthy during the investigation, including the medical history.