By Bernard L. Horecker, Earl R. Stadtman
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Strains of Staphylococcus, Gaffkya, Flavobacterium, Achromobacter, and Alcaligenes also show sequen tial feedback inhibition of DAHP synthetase by either prephenate or chorismate (67). The DAHP synthetase from Xanthomonas on the other hand, is inhibited strongly by chorismate and only to a small extent by prephenate. Different sensitivities of the DAHP synthetases from different organisms to chorismate and prephenate may reflect different points of feedback inhibition by phenylalanine and tyrosine in that, according to the organism, either chorismate or prephenate forms a branch point leading to phenylalanine or tyrosine (see later).
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