By Claire Dulieu, Denis Poncelet, Ronald J. Neufeld (auth.), Willem M. Kühtreiber PhD, Robert P. Lanza MD, William L. Chick MD (eds.)
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Additional resources for Cell Encapsulation Technology and Therapeutics
It is important to note that in the operation of a bioreactor, the gas to bulk liquid oxygen transfer is the only resistance that can be controlled. Varying the aeration rate will affect the gas to liquid oxygen transfer, which in turn will affect the transfer of oxygen from the bulk liquid to the cell. Researchers have, therefore, focused on measuring the mass transfer coefficient kp, under various operating conditions, for the purpose of developing useful correlations that may be employed as scale-up criteria for animal cell bioreactors.
Applied Biochemistry and Biotechnology. 73(1),59-77. Shigeta J. 1995. Germination and Growth of Encapsulated Somatic Embryos of Carrot for Mass Propagation. Biotechnol. Tech. 10 (9), 771-776. Siegel MH and Merchuk Je. 1988. Mass Transfer in a Rectangular Air-Lift Reactor: Effects of Geometry and Gas Circulation. 32,1128-1137. Stegemann JP and Sefton MV. 1996. Video Analysis of Submerged Jet Microencapsulation Using HRMAMMA. Canadian Journal of Chemical Engineering. 74,518-525. Svec F and Gemeiner P.
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