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By Gordon Morrison

A toddler crouches beside a meadow brook, and a drop of water collects and falls from the child's fingertip to proceed on its trip. the place does that trip start? excessive within the sky, rain clouds are parting. Water trickles and flows down the mountain, amassing in an upland lavatory, seeping via a beaver's dam, dashing over rocks, passing many vegetation and animals alongside its winding way—each depending on water and different environments it shapes to stay. writer and illustrator Gordon Morrison has captured a unmarried second in time, revealing the direction and impact of water, and alluring readers to pause and examine the area round them during this appealing and lyrical appreciation of nature and the source that makes all of it possible—a drop of water.

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Cule called the ‘pseudomonas quinolone Pseudomonas aeruginosa is an opporsignal’ (PQS) to send messages to other tunistic human pathogen that is a parbacteria of the same species. The surprise ticular problem in the lungs of cystic is that, rather than being secreted as single fibrosis patients. Greater understanding molecules, PQS is released in bubble-like about how these bacteria communicate ‘vesicles’ that also contain antibacterial with each other and attack host cells agents and probably toxins aimed at host could lead to novel treatment strategies tissue cells as well.

Aeruginosa, some of elastic-sheet model of microtubule structure. another bacterial communication system — which have potent antibacterial activity. The Such a model was previously proposed3 and one aimed at enemies rather than friends. membrane vesicles, in addition to signalling to applied 3–5 by Flyvbjerg and colleagues in earlier papers. The authors apologize for the oversight Many Gram-negative bacteria release minute kindred P. aeruginosa cells, showed potent in not citing these earlier quantitative studies.

Eur. Biophys. J. cles consist of a lipid bilayer surrounding an was due to quinolines rather than to the pro27, 501–513 (1998). aqueous core and they can therefore transport tein component of the vesicles. , Jánosi, I. , Taveau, I. & Flyvbjerg, H. Cell Struct. Funct. 24, 299–303 (1999). The production of the vesicles seems to be lipid-soluble toxins (lipopolysaccharide endo5. Jánosi, I. , Chrétien, D. & Flyvbjerg, H. Biophys. J. 83, toxin) on their surface and protein toxins in regulated by PQS, because when PQS synthesis 1317–1330 (2002).

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